Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes

Original research article by S. Endele et al. (2010)

Read the abstract here.

The GRINB2 gene  is responsible for transmitting information in the brain. 468 people with intellectual disability were screened for a GRIN2B change. Four were found to have a change in this gene. None of the changes were inherited from a parent.